Chemicals
Comparative analysis of estimated and measured BCF data (OECD 305)
Literature study with a special focus on differential accumulation of (mixtures of) stereoisomers
Bioaccumulation potential of chemicals is frequently assessed from bioconcentration, conventionally measured according to OECD 305 (Bioaccumulation: Flow-through Fish Test) (OECD,1996) and expressed as Bioconcentration Factor (BCF). These studies deliberately reduce the manifold uptake and elimination mechanisms in aquatic organisms to respiratory absorption via gills and diffusion through the ski...read more